A dual-targeting hybrid platinum(IV) prodrug for enhancing efficacy.
نویسندگان
چکیده
A multifunctional hybrid platinum(IV) prodrug, which consists of both the mitochondria-targeting drug DCA and the DNA-crosslinking drug cisplatin, was synthesized and tethered to a carrier polymer to further self-assemble into micelles for intracellular delivery.
منابع مشابه
Chalcoplatin, a dual-targeting and p53 activator-containing anticancer platinum(IV) prodrug with unique mode of action.
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عنوان ژورنال:
- Chemical communications
دوره 48 87 شماره
صفحات -
تاریخ انتشار 2012